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A potent long-acting amide-class local anaesthetic with a 4–8 hour duration of action, which is doubled by adding adrenaline/epinephrine.

Adverse effects
• CNS toxicity—Nervousness, perioral tingling, tinnitus, tremor, dizziness, blurred vision and seizures, followed by drowsiness, loss of consciousness, respiratory depression and apnoea.
• Cardiotoxicity—Hypotension, bradycardia, arrhythmias and cardiac arrest.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.


Bupivacaine, see there.
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.


The long-acting local anaesthetic drug BUPIVACAINE. The effect lasts for about 4 hours.
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005
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References in periodicals archive ?
If you have a painful procedure and you're in an OR setting where you give Marcaine [bupivacaine], put that in at the end of the procedure for short-term postoperative pain relief." After the procedure, it's better not to apologize for causing pain or if the procedure didn't go well.
1 choice for local anesthesia in nail surgery followed by bupivacaine (Marcaine) in a distant second.
After making 2 cc lidocaine (Jetmonal, Adeka, Samsun, Turkey) as test dose with infusion in the epidural catheter and determining that it is the right space, 10 cc 0.25 % bupivacaine (Marcaine, AstraZeneca, UK) was applied through the epidural catheter.
To provide patient comfort, the defendant injected Marcaine anesthetic through a syringe and needle.
Sixty suitable patients who accepted to participate in the study and who gave written consent were randomized into two groups with random numbers table including group P (n= 30): Ultrasound-guided bilateral Posterior QLB with 0.3 mL/kg 0.25% bupivacaine (Marcaine %0.5 AstraZeneca, Istanbul, Turkey) + IV patient-controlled analgesia (PCA) tramadol (Tramosel[R], Haver, Istanbul, Turkey) and group L (n= 30): Ultrasound-guided bilateral Lateral QLB with 0.3 mL/kg 0.25% bupivacaine + IV patient-controlled analgesia (PCA) tramadol (Figure 1).
All femoral nerve blocks were undertaken with a nerve stimulator and 20 mL of 0.25% marcaine infiltrated.
We used a mixture of 2% lidocaine with marcaine local anaesthesia as a subcutaneous ring block at the base of the penis as per the WHO Manual for Male Circumcision under Local Anaesthesia.
Analgesie peridurale au cours du travail: etude comparative de l'association fentanyl-marcaine et de la marcaine seule.
After injection of 15mg (3 ml) heavy Marcaine into the subarachnoid space, 3cm of epidural catheter was placed into epidural space.
The pins were inserted under local anesthesia of lidocaine and/or Marcaine after the scalps of patients were shaved and prepared routinely.