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a shorthaired, medium-sized cat with long hindlegs, prominent hindquarters and some degree of taillessness which can range from absolute, with only a hollow at the end of the spine ('rumpies'), to a short, immobile tail only a few coccygeal vertebrae long and not projecting above the back ('rumpyriser'), to one longer, mobile, but often kinked or otherwise deformed ('stumpy'). Occasionally a normal looking, but abnormally short, tail is produced ('longie'). The Manx gene which is dominant is often associated with other deformities of the lower gastrointestinal tract, such as atresia ani, or spine, such as spina bifida, and many Manx have unusual hindleg gaits as a result. All Manx are heterozygotes, as the trait is lethal, prenatally, in the homozygous state. The usual breeding is Manx to normal, to avoid such losses, but Manx litters are normally very small. The breed is also affected by a hereditary corneal edema.
a strain of calicivirus, isolated from and named after a Manx cat, at one time incriminated in the etiology of the feline urological syndrome; its significance is unclear.