Mantoux test


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Mantoux test

 [man-too´]
a tuberculin skin test in which a solution of 0.1 mL of PPD-tuberculin containing 5 tuberculin units is injected intradermally into either the anterior or posterior surface of the forearm. The test is read 48 to 72 hours after injection. The size of the area of any induration at the site of injection, in combination with patient risk factors, is used to determine whether the test is positive, that is, whether exposure to or infection with Mycobacterium tuberculosis (the agent causing tuberculosis) or a related organism has occurred.

tu·ber·cu·lin test

application of the skin test to the diagnosis of infection by Mycobacterium tuberculosis in which tuberculin or its "purified" protein derivative serves as an antigen (allergen); injection of graduated doses of tuberculin or of purified protein derivative into the skin, most often by means of a needle and syringe (Mantoux test) or by means of tines (tine test); test material may also be applied by means of a "patch" in which it is absorbed but this method (patch test) is considered less reliable; the test is read on the basis of induration and erythema, the former being considered the more diagnostic of infection with the tubercle bacillus (M. tuberculosis); the test does not distinguish between infection in a resistant person without disease and a person with clinical manifestations of disease.

Mantoux test

(măn-to͞o′, män-)
n.
A tuberculin test in which a small amount of tuberculin is injected under the skin.

Mantoux test

An intracutaneous test used to diagnose TB based on hypersensitivity to tuberculin, a concentrate of TB antigen, the standard preparation of which is purified protein derivative.

Mantoux test

Mantoux tuberculin skin test An intracutaneous test used to diagnose TB based on hypersensitivity to tuberculin, a concentrate of TB antigen, the standard preparation of which is PPD–purified protein derivative. See PPD, Tuberculin test, Tuberculosis.

tu·ber·cu·lin test

(tū-bĕr'kyū-lin test)
A dermatologic procedure in which tuberculin or its purified protein derivative (PPD) is injected into the skin; the test is read on the basis of local induration occurring in 48-72 hours.

Mantoux test

A skin test for resistance to TUBERCULOSIS in which a small quantity of a sterile liquid derived from a culture of tubercle bacilli (tuberculin) is injected into the skin and the local reaction noted. A negative result suggests susceptibility to tuberculosis and may prompt vaccination with BCG. The test is now performed by a rapid multiple puncture technique, similar to the Heaf test, but using disposable, multiple-tine test units. (Charles Mantoux, 1887–1947, French physician).
References in periodicals archive ?
d) Advices patient to do Mantoux test and if positive, start patient on Anti-Tubercular treatment.
Thus, a fair strength of agreement was found between detection of tuberculous endometritis by PCR, Mantoux test and ELISA.
Of the 150 control subjects (Table 1) 0, were found to be positive for both the Mantoux test and the in vitro lymphocyte stimulation assay, 23 (i.e.
Mantoux test (MT) was done in all patients with intradermal injection of 10 TU of purified protein derivatives (PPD) on the flexor surface of forearm and induration was measured after 72 hours.
Clinically diagnosed cases of pulmonary TB undergoing sputum smear examination, Mantoux test and X-ray chest were included in the study.
(Mantoux test and sputum test for tubercle bacilli were negative.) Vitamin B12 was 554 pg/mL and folate 7 ng/mL; ANA test was negative, and thyroid hormone profile and cortisol showed normal levels.
The results of the C-antineutrophil cytoplasmic antibody (C-ANCA) test, Mantoux test, and chest x-ray were normal.
A full blood count showed lymphocytosis, the Mantoux test was strongly positive with cross-sectional (horizontal) induration of 16 mm, the chest radiograph showed some hilar prominence, and fine-needle aspiration cytology (FNAC) showed acid-fast bacilli on Ziehl-Neelsen staining (Fig.
The poor yield of the Mantoux test, particularly in cases of TBM, has been mentioned earlier in literature.18 Similarly, the use of CT scan in cases of TBM has been associated with a non- specific diagnostic yield.19 However, some authors have repor ted the significance of basal enhancement, hydrocephalus, infarction and high density within the basal cisterns on non-contrast CT, and their value as a clue to the diagnosis of TBM.20 In our study, 66% of the patients with TBM had hydrocephalus on CT scan at the time of presentation.
His Mantoux test turned out to be negative indicating his rectal disease could be primary in the backdrop of his negative HIV status.