Is electric arc welding linked to manganism
or Parkinson's disease?
Some diseases are associated with high levels of these elements in drinking water, for example, excess iron can cause genetic disorder (haemochromatosis), while manganese overload can cause neurologic disorder, such as the syndrome known as "manganism
" which resemble Parkinson's disease and includes symptoms like neurobehavioral manifestations, weakness and rapid postural tremor and others [25-27].
Estimating the prevalence of clinical manganism
using a cascaded screening process in a South African manganese smelter.
Researchers have pointed out that the consequences of exposure to manganese in the workplace and uptake of this element in the body will bring about the central nervous system disorder, which would be called manganism
, as the complications; there are many similarities with Parkinson's disease [5-12].
Dopaminergic neurons in the substantia nigra are especially sensitive to Mn toxicity; thus, accumulated Mn may cause manganism
, a disease condition with etiology almost identical with PD.
Haldre et al., "Irreversible motor impairment in young addicts--ephedrone, manganism
or both?" Acta Neurologica Scandinavica, vol.
The plaintiff had been exposed to manganese, but developed Parkinson's, not manganism
is caused by exposure to manganese, Parkinson's is not.
Occupational exposure to Mn can result in neurological disorder, called manganism
, and is similar to Parkinson disease.
According to the World Health Organization's 2011 guidelines for drinking-water quality, it would require exposure to high levels of manganese over a long period before manganism
High exposures to airborne Mn (such as in a ferromanganese plant occupational setting) can lead to a neuro-degenerative disease known as manganism
, which has symptoms similar to those of Parkinson's disease [15, 24, 25].
A Canadian study (Finkelstein and Jerrett 2007) did not find associations with a land use regression-derived traffic-related pollution measure for N[O.sub.2] but reported small positive associations with PD for manganese, a metal that has been related to a syndrome with Parkinsonian features called "manganism
" distinct from idiopathic PD (Rivera-Mancfa et al.
Mn intoxication can lead to a disorder known as manganism
characterized by severe neurological deficits that often resemble the involuntary extrapyramidal symptoms associated with Parkinson's disease and may evolve to more Parkinson-like syndrome .