methaqualone

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methaqualone

 [meth″ah-qua´lōn]
a nonbarbiturate compound formerly used as a sedative and hypnotic; now found only as a drug of abuse. See drug abuse.

methaqualone

(mĕth′ə-kwā′lōn′)
n.
A potentially habit-forming drug, C16H14N2O, formerly used as a sedative and hypnotic.

methaqualone

An addictive Schedule-II hypnotic-sedative quinazolone with barbiturate-like effects which, when it was legal, was used to reduce anxiety and tension. It was a popular drug of abuse, and it was linked to physical or psychologic dependence.

Clinical findings
Delirium, headache, nausea, pyramidal signs, convulsions, renal and cardiac failure; rarely, aplastic anaemia.
 
Route
Oral, injected, sniffed, smoked.
 
Management of overdose
Haemoperfusion.

Toxic range
> 8 µg/mL, serum; > 300 µg/L, urine.
 
T1/2
20–60 hours.
 
Specimen
Serum, random urine.
 
Method
GC.

methaqualone

Quaalude, 'ludes' Substance abuse An addictive Schedule II hypnotic-sedative quinazolone with barbiturate-like effects; methaqualone was a popular drug of abuse and linked to physical or psychologic dependence Clinical Delirium, headache, nausea, pyramidal signs, convulsions, renal and cardiac failure; rarely, aplastic anemia Route Oral, injected, sniffed, smoked Used for Anxiety, tension Management Hemoperfusion. See Controlled drug substance.
References in periodicals archive ?
Methaqualone (Mandrax) and marijuana (dagga) are widely trafficked in Western Cape, but the drug of choice among dealers is crystal methamphetamine (tik).
'I started when I was 12 years old with dagga and I was 16 when I used mandrax, from 34 years I smoke crack.
For the cannabis question, the term 'dagga' (the common South African name for cannabis) was added, as was mandrax under sedatives, and tik under amphetamine-type stimulants.
The GCPCD also reports the seizure of 2,955 kilos of hashish, 2,619 kilos of marijuana (slightly less than 2008), 6 kilos of cocaine, 4.4 kilos of heroin, 20 kilos of mandrax, and 113 marijuana plants.
In terms of treatment demand, cannabis abuse alone increased from 14% in 1999 to 17% in 2005 of all treatment demand, while cannabis mixed with mandrax has remained stable from 7% in 1999 to 7% in 2005 of treatment demand of all drugs.
The port of Dar es Salaam is also a point of entry for Mandrax (Methaqualone) from India, Nepal and Kenya headed toward South Africa.
In 2008, law enforcement elements seized 800 gm and 253 tabs of non-designated psychotropic substances while in 2009, the ANU seized more than 9000 tabs of mandrax (3197), rohypnol (1714), diazepam (243) and valium (2554).
Mozambique is a transit country for illegal drugs such as hashish, herbal cannabis, cocaine, and heroin consumed primarily in Europe, and for mandrax (methaqualone) consumed primarily in South Africa.
South Africa may also be the world's largest consumer of Mandrax, a variant of methaqualone, an amphetamine-type stimulant.
Drugs like cocaine, heroin, khat, and Mandrax, as well as raw opium pass through Tanzania's porous borders.
According to the crime report during police search a 21-year-old female was found in possession of 228 mandrax tablets, adding that further police investigations led to the arrest of the second suspect, a 47-year-old man.
That "public relations" outing, Goswami said, was intended to help persuade the drug dealer to accept the Akashas' offer for the purchase of large amounts of a substance used in manufacturing Mandrax, an illegal sedative.