Malate shuttle | definition of Malate shuttle by Medical dictionary
malate-aspartate shuttle (redirected from Malate shuttle)
a mechanism for the transfer of NADH, reducing equivalents from the cytosol into the mitochondria using two isozymes of malate dehydrogenase and aspartate aminotransferase.
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Malate dehydrogenase (MDH), a key enzyme in the tricarboxylic acid cycle (TCA), plays important metabolic roles in aerobic energy producing pathways and in malate shuttle
(Figure 1) .