major crossmatch

major crossmatch

The testing of a recipient’s serum against potential donor red cells to detect ABO incompatibility and other major antibodies.

crossmatch

Serologic crossmatch Transfusion medicine An agglutination test that determines donor-recipient blood compatibility. See Electronic crossmatch, Immediate spin crossmatch, Major crossmatch, Minor crossmatch.
Crossmatch
Major crossmatch Patient serum–which may contain antibodies is cross-reacted against the donor's red cells and
Minor crossmatch Patient RBCs are incubated with donor serum, this is of less clinical significance; it reveals donor antibodies against uncommon antigens–eg Cw, -Wra, -Lia 
References in periodicals archive ?
In major crossmatch, 2 drops of donor cells and 2 drops of recipient serum are put and mixed.
Pretransfusion compatibility testing continues, but it includes a major crossmatch (a serologic reaction between intended recipient serum and donor cells) only if one of the following conditions is met: 1) the patient's atypical antibody screen is positive; 2) the transfusion service's card file indicates a history of an antibody or a prior transfusion reaction; or 3) the patient has a positive direct Coombs test.
G3.000 A major crossmatch must use donor cells from the originally attached donor or component segment.