Magnetic Resonance Venography

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Magnetic Resonance Venography

Synonym/acronym: MRV.

Common use

To visualize and assess blood flow in diseased and normal veins toward diagnosis of vascular disease and to monitor and evaluate therapeutic interventions.

Area of application



Can be done with or without IV contrast (gadolinium).


Magnetic resonance imaging (MRI) is very useful when the area of interest is soft tissue. The technology does not involve radiation exposure and is considered safer than other imaging methods such as radiographs and computed tomography (CT). MRI uses a magnet and radio waves to produce an energy field that can be displayed as an image of the anatomic area of interest based on the water content of the tissue. The magnetic field causes the hydrogen atoms in tissue to line up, and when radio waves are directed toward the magnetic field, the hydrogen atoms absorb the radio waves and change their position. This change in the energy field is detected by the equipment, and an image is generated by the equipment’s computer system. MRI produces cross-sectional images of the vessels in multiple planes without the use of ionizing radiation or the interference of bone or surrounding tissue. Images can be obtained in two-dimensional (series of slices) or three-dimensional sequences. Standard or closed MRI equipment has the appearance of an open tube or tunnel; open MRI equipment has no sides and provides an alternative for people who suffer from claustrophobia, pediatric patients, or patients who are obese. IV gadolinium-based contrast media may be used to better visualize the vessels and tissues in the area of interest. Clear, high-quality images of abnormalities and disease processes significantly improve the diagnostic value of the study.

Magnetic resonance venography (MRV) is an accurate, noninvasive technique used to detect deep vein thrombosis. This application of MRI provides images of blood flow in diseased and normal veins. In patients who are allergic to iodinated contrast medium, MRV is used in place of venography or CT venography. MRV is particularly useful for visualizing vascular abnormalities, thrombosis, and other pathology. MRV can be accomplished with a contrast-enhanced (CE) or non–contrast-enhanced method. Special imaging sequences allow the visualization of moving blood within the venous system. Two common techniques to obtain images of flowing blood are time-of-flight (TOF) and steady-state free precession (SSFP). In TOF imaging, incoming blood makes the vessels appear bright, and surrounding tissue is suppressed. SSFP is generally used for assessment of veins in the chest, abdomen, and pelvis. Although the initial evaluation of the iliac and lower extremity veins is usually accomplished with sonography, MRV is more efficient in detecting venous thrombus in the pelvic and calf veins, especially in obese patients and those with chronic asymptomatic thrombus.

This procedure is contraindicated for

  • high alert Patients who are pregnant or suspected of being pregnant, unless the potential benefits of MRI far outweigh the risks to the fetus and mother. In pregnancy, gadolinium-based contrast agents (GBCAs) cross the placental barrier, enter the fetal circulation, and pass via the kidneys into the amniotic fluid. Although no definite adverse effects of GBCA administration on the human fetus have been documented, the potential bioeffects of fetal GBCA exposure are not well understood. GBCA administration should therefore be avoided during pregnancy unless no suitable alternative imaging is possible and the benefits of contrast administration outweigh the potential risk to the fetus.
  • high alert Patients with moderate to marked renal impairment (glomerular filtration rate less than 30 mL/min/1.73 m2). Patients should be screened for renal dysfunction prior to administration. The use of GBCAs should be avoided in these patients unless the benefits of the studies outweigh the risks and if essential diagnostic information is not available using non–contrast-enhanced diagnostic studies.
  • high alert Patients with cardiac pacemakers that can be deactivated by MRI.
  • high alert Patients with metal in their body, such as dental amalgams, metallic body piercing items, tattoo inks containing iron (including tattooed eyeliners), shrapnel, bullet, ferrous metal in the eye, certain ferrous metal prosthetics, valves, aneurysm clips, IUD, inner ear prostheses, or other metallic objects; these items can impair image quality. Metallic objects are also a significant safety issue for patients and health-care staff in the examination room during performance of an MRI. The MRI equipment consists of an extremely powerful magnet that can inactivate, move, or shift metallic objects inside a patient. Many metallic objects currently used in health-care procedures are made of materials that do not interfere with MRI studies; it is important for patients to provide specific information regarding medical procedures they have undergone in order to identify whether their device is safe to undergo MRI. Required information includes the date of the procedure and identification of the device. Metallic objects are not allowed inside the room with the MRI equipment because items such as watches, credit cards, and car keys, can become dangerous projectiles.
  • high alert Patients with transdermal patches containing metallic components. The patch’s liner contains a metal that controls absorption of the substance from the patch (e.g., drugs, nicotine, steroids, hormones). The patch may cause burns to the skin related to energy conducted through the metal which is converted to heat during the MRI. Other metallic objects on the skin may also cause burns.
  • high alert Patients who are claustrophobic.


  • Detect peripheral vascular disease (PVD)
  • Detect axillary vein disease
  • Detect cerebral vein disease
  • Detect pulmonary vein disease
  • Evaluate iliac and lower-extremity vein disease
  • Evaluate postoperative venous sites and bypass grafts
  • Identify deep vein thrombus in postsurgical patients
  • Monitor and evaluate the effectiveness of medical or surgical treatment

Potential diagnosis

Normal findings

  • Normal blood flow in the area being examined

Abnormal findings related to

  • Cerebral vein thrombosis
  • Deep vein thrombosis
  • Pulmonary emboli
  • PVD
  • Tumor invasion of a vein
  • Vascular abnormalities
  • Vein occlusion
  • Vein stenosis

Critical findings

  • Cerebral emboli
  • Occlusion
  • Pulmonary emboli
  • Tumor with significant mass effect
  • It is essential that a critical finding be communicated immediately to the requesting health-care provider (HCP). A listing of these findings varies among facilities.

  • Timely notification of a critical finding for lab or diagnostic studies is a role expectation of the professional nurse. Notification processes will vary among facilities. Upon receipt of the critical value the information should be read back to the caller to verify accuracy. Most policies require immediate notification of the primary HCP, Hospitalist, or on-call HCP. Reported information includes the patient’s name, unique identifiers, critical value, name of the person giving the report, and name of the person receiving the report. Documentation of notification should be made in the medical record with the name of the HCP notified, time and date of notification, and any orders received. Any delay in a timely report of a critical finding may require completion of a notification form with review by Risk Management.

Interfering factors

  • Factors that may impair clear imaging

    • Metallic objects (e.g., jewelry, body rings, dental amalgams) within the examination field, which may inhibit organ visualization and cause unclear images.
    • Inability of the patient to cooperate or remain still during the procedure because of age, significant pain, or mental status.
    • Patients with extreme cases of claustrophobia, unless sedation is given before the study.
  • Other considerations

    • If contrast medium is allowed to seep deep into the muscle tissue, vascular visualization will be impossible.

Nursing Implications and Procedure


  • Positively identify the patient using at least two unique identifiers before providing care, treatment, or services.
  • Patient Teaching: Inform the patient this procedure can assist in assessing the vascular system.
  • Obtain a history of the patient’s complaints or clinical symptoms, including a list of known allergens, especially allergies or sensitivities to latex, anesthetics, contrast medium, or sedatives. Patients with a known hypersensitivity to contrast medium may benefit from premedication with corticosteroids and diphenhydramine.
  • Obtain a history of the patient’s cardiovascular system, symptoms, and results of previously performed laboratory tests and diagnostic and surgical procedures. Obtain a history of renal dysfunction if the use of GBCA is anticipated.
  • Ensure the results of BUN, creatinine, and eGFR (estimated glomerular filtration rate) are obtained if GBCA is to be used.
  • Determine if the patient has ever had any device implanted into his or her body, including copper intrauterine devices, pacemakers, ear implants, and heart valves.
  • Obtain occupational history to determine the presence of metal in the body, such as shrapnel or flecks of ferrous metal in the eye (which can cause retinal hemorrhage).
  • Note any recent procedures that can interfere with test results.
  • Record the date of the last menstrual period and determine the possibility of pregnancy in perimenopausal women.
  • Obtain a list of the patient’s current medications, including herbs, nutritional supplements, and nutraceuticals (see Effects of Natural Products on Laboratory Values online at DavisPlus).
  • Review the procedure with the patient. Address concerns about pain related to the procedure and explain that no pain will be experienced during the test, but there may be moments of discomfort. Reassure the patient that if contrast is used, it poses no radioactive hazard and rarely produces side effects. Inform the patient the procedure is performed in an MRI department by an HCP who specializes in this procedure, with support staff, and takes approximately 30 to 60 min.
  • Inform the patient that the technologist will place him or her in a supine position on a flat table in a large cylindrical scanner.
  • Tell the patient to expect to hear loud banging from the scanner and possibly to see magnetophosphenes (flickering lights in the visual field); these will stop when the procedure is over.
  • Explain that an IV line may be inserted to allow infusion of IV fluids such as saline, anesthetics, contrast medium, or sedatives.
  • Sensitivity to social and cultural issues, as well as concern for modesty, is important in providing psychological support before, during, and after the procedure.
  • Instruct the patient to remove external metallic objects from the area to be examined prior to the procedure.
  • Note that there are no food, fluid, or medication restrictions unless by medical direction.


  • Potential complications:
  • Injection of the contrast is an invasive procedure. Complications are rare but do include risk for allergic reaction related to contrast reaction; cardiac arrhythmias; hematoma related to blood leakage into the tissue following needle insertion; bleeding from the puncture site related to a bleeding disorder, or the effects of natural products and medications known to act as blood thinners; vascular or nerve injury that might occur if the needle strikes a nerve or nearby blood vessel; or infection that might occur if bacteria from the skin surface is introduced at the puncture site.

  • Observe standard precautions, and follow the general guidelines in Patient Preparation and Specimen Collection. Positively identify the patient.
  • Ensure that the patient has removed external metallic objects from the area to be examined prior to the procedure.
  • Administer ordered prophylactic steroids or antihistamines before the procedure if the patient has a history of allergic reactions to any substance or drug.
  • Avoid the use of equipment containing latex if the patient has a history of allergic reaction to latex.
  • Have emergency equipment readily available.
  • Instruct the patient to void prior to the procedure and to change into the gown, robe, and foot coverings provided.
  • Instruct the patient to cooperate fully and to follow directions. Instruct the patient to remain still throughout the procedure because movement produces unreliable results.
  • Supply earplugs to the patient to block out the loud, banging sounds that occur during the test. Instruct the patient to communicate with the technologist during the examination via a microphone within the scanner.
  • Apply MRI-safe electrodes to the appropriate sites if an electrocardiogram or respiratory gating is to be performed in conjunction with the scan.
  • Establish IV fluid line for the injection IV fluids such as saline, anesthetics, contrast medium, or sedatives.
  • Administer an antianxiety agent, as ordered, if the patient has claustrophobia. Administer a sedative to a child or to an uncooperative adult, as ordered.
  • Assist the patient onto the examination table and into the appropriate position for imaging to begin.
  • Imaging can begin shortly after the injection, if contrast is used.
  • Ask the patient to inhale deeply and hold his or her breath while the images are taken, and then to exhale after the images are taken.
  • Instruct the patient to take slow, deep breaths if nausea occurs during the procedure.
  • Monitor the patient for complications related to the procedure (e.g., allergic reaction, anaphylaxis, bronchospasm).
  • Remove the needle or catheter and apply a pressure dressing over the puncture site.
  • Observe/assess the needle/catheter insertion site for bleeding, inflammation, or hematoma formation.


  • Inform the patient that a report of the results will be made available to the requesting HCP, who will discuss the results with the patient.
  • Observe for delayed allergic reactions, such as rash, urticaria, tachycardia, hyperpnea, hypertension, palpitations, nausea, or vomiting.
  • Instruct the patient to immediately report symptoms such as fast heart rate, difficulty breathing, skin rash, itching, chest pain, persistent right shoulder pain, or abdominal pain. Immediately report symptoms to the appropriate HCP.
  • Instruct the patient in the care and assessment of the injection site.
  • Instruct the patient to apply cold compresses to the puncture site as needed to reduce discomfort or edema.
  • Recognize anxiety related to test results. Discuss the implications of abnormal test results on the patient’s lifestyle. Provide teaching and information regarding the clinical implications of the test results, as appropriate. Provide contact information, if desired, for the American Heart Association (, the NHLBI (, or Legs for Life (
  • Reinforce information given by the patient’s HCP regarding further testing, treatment, or referral to another HCP. Answer any questions or address any concerns voiced by the patient or family.
  • Depending on the results of this procedure, additional testing may be performed to evaluate or monitor progression of the disease process and determine the need for a change in therapy. Evaluate test results in relation to the patient’s symptoms and other tests performed.

Related Monographs

  • Related tests include angiography of the body area of interest, BUN, CT angiography, creatinine, d-dimer, US arterial Doppler carotid, US venous Doppler extremity studies, and venography lower extremity studies.
  • Refer to the Cardiovascular System table at the end of the book for related tests by body system.
Handbook of Laboratory and Diagnostic Tests, © 2013 Farlex and Partners
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References in periodicals archive ?
Transverse venous sinus stenosis CSF, cerebrospinal fluid; IIH, idiopathic intracranial hypertension; LP, lumbar puncture; MRI, magnetic resonance imaging; MRV, magnetic resonance venography.
Abbreviations AM: Acute mastoiditis AOM: Acute otitis media BA: Bezold's abscess CCOM: Cholesteatomatous chronic otitis media CRP: C-reactive protein CT: Computed tomography EEC: Extracranial complication ENT: Ear, nose, throat ESR: Erythrocyte sedimentation rate ICC: Intracranial complication LST: Lateral sinus thrombosis MRI: Magnetic resonance imaging MRV: Magnetic resonance venography WBC: White blood count.
Haacke, "A comparative study of magnetic resonance venography techniques for the evaluation of the internal jugular veins in multiple sclerosis patients," Magnetic Resonance Imaging, vol.
Other neuroimaging findings--magnetic resonance imaging (MRI), magnetic resonance angiogram (MRA), magnetic resonance venography (MRV), and computed tomography angiography (CTA)--were consistent with moyamoya disease and confirmed by cerebral angiography (Figures 1, 2).
Unusual deep venous thrombosis sites: Magnetic resonance venography in patients with negative compression ultrasound and symptomatic pulmonary embolism.
Parker, "High resolution magnetic resonance venography at 3 Tesla: optimized acquisition, reconstruction, and post-processing," in Proceedings of the International Society for Magnetic Resonance in Medicine (ISMRM '06), p.
(1-3) The current gold standard to diagnose CVT is the combination of MRI to visualise the thrombosed vessel and magnetic resonance venography to detect the non-visualisation of the same vessel.
However, careful examination of both studies led us to suspect a venous malformation; therefore, magnetic resonance venography (MRV) was ordered.
Preoperative diagnosis can be made on ultrasound, computerized tomography, magnetic resonance imaging or magnetic resonance venography. In our case the sonologist mistook the aberrant testis as hydrocele of the cord.
These findings were confirmed on magnetic resonance imaging (MRI), angiography (MRA) and magnetic resonance venography (MRV) (Figs 1b, 3a, 3b.) Digital substraction angiography (DSA) confirmed a mural type of VGAM supplied by the left posterior medial choroidal artery.

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