However, the most effective topical agent for the ear which can prevent and even treat chondritis is mafenide
(sulfamylon) cream because of its excellent ability to penetrate the eschar and the cartilage and has a broad antibacterial spectrum with good bacteriostatic action.
Nowadays, prescription drugs such as sulfadiazine silver and mafenide
, which are effective in relieving symptoms and promoting healing, are widely used in burn.
In vitro toxicity and activity of Dakin's solution, mafenide
acetate, and amphotericin B on filamentous fungi and human cells.
Topical 5 percent mafenide
acetate solution (5% Sulfamylon Solution) was found to be bactericidal against many nosocomial Acinetobacter isolates, and wound-care protocols suggest its use in place of normal saline for washing wounds .
Off-label drug use in WOC nursing: Issues related to use of mafenide
acetate to treat infected chronic wounds.
Limited success has also been seen with non-antibiotic remedies such as chlorohexidine, nitrofurazone, PVP-I, mafenide
(18-24) Povidone iodine has a bacteriostatic therapeutic life of 4 hours following a single topical application, mafenide
acetate 12 hours and silver sulphadiazine (AgSD) 1% up to 36 hours.
acetate is a drug with good penetration that can prevent infection, and Dr.
The wound was cleansed, hemostasis obtained, and the wound was dressed with gauze dressings soaked in 5% solution of mafenide