Madelung disease

mul·ti·ple sym·met·ric lip·o·ma·to·sis

accumulation and progressive enlargement of collections of adipose tissue in the subcutaneous tissue of the head, neck, upper trunk, and upper portions of the upper extremities; seen primarily in adult males and of unknown cause.
Farlex Partner Medical Dictionary © Farlex 2012

Madelung disease

Generalized symmetrical deposits of fatty tissue (lipomas) on the upper back, shoulders, and neck. Synonym: Madelung neck
Medical Dictionary, © 2009 Farlex and Partners


Otto Wilhelm, German surgeon, 1846-1926.
Madelung deformity - a distal radial ulnar subluxation due to relative deficiency of axial growth of the medial side of the distal radius. Synonym(s): carpus curvus
Madelung disease - accumulation and progressive enlargement of adipose tissue in the subcutaneous tissue of the head, neck, upper trunk, and upper portions of the upper extremities. Synonym(s): multiple symmetric lipomatosis
Madelung lipoma - fatty tumor.
Madelung neck - multiple symmetric lipomatosis confined to the neck.
Madelung subluxation - incomplete dislocation or luxation.
Medical Eponyms © Farlex 2012
References in periodicals archive ?
Madelung disease: distribution of cervical fat and preoperative findings at sonography, MR, and CT.
[3] Two rare distinct familial types of lipomatosis have been identified, which are FML and multiple symmetric lipomatosis (MSL) also known as Madelung disease. Clinically, the most prominent difference between these two types of lipomatosis is that FML is marked by discrete lipomas that predominate on the extremities and generally absent from neck and shoulders, whereas MSL is a nonencapsulated, diffuse lipomatosis infiltration of underlying tissue (i.e., often is most prominent in neck and shoulder regions).
[Literature review of Madelung disease: 1 case report].
The adipose deposits, sparing the distal extremities in this patient, were consistent with so-called multiple symmetric lipomatosis (MSL), also known as Madelung disease.
Yang, "Madelung disease," Canadian Medical Association Journal, vol.
Goldszmidt, "Case 143: Madelung disease," Radiology, vol.
The patient was diagnosed as having Madelung disease based on the physical examination findings.
Madelung disease (benign symmetric lipomatosis) is a rare disease of uncertain etiology, mainly reported in Mediterranean and eastern European populations.
However, Madelung disease may be associated with serious medical problems: difficulties in limb movements, difficulties in turning of the head, difficulties in deglutition, hoarseness, dyspnea, or sleep apnea caused by airway compression.
Patients with Madelung disease have soft masses in the parotid area ("hamster cheeks"), cervical region ("horse collar"), and back ("hump back").
(9) Lipomas usually occur sporadically, but some are associated with several inherited disorders, including multiple lipomatosis, Gardner syndrome, and Madelung disease. (3) Recurrences, which have been reported in about 5% of patients, are more common when the lipoma is associated with generalized lipomatosis, when the mass is not completely removed at surgery, or when the tumor is a well-differentiated liposarcoma incorrectly diagnosed as a benign lipoma.