Directing credits include Birdbath for McKee Place Productions, La Ronde for The Rep and Mad Honey
for Unseam'd Shakespeare.
Episodic LBBB is associated with different clinical situations such as bradycardia, tachycardia, anesthesia, acute pulmonary embolism, intrathoracic pressure changes, chest trauma, cardiac interventional procedures, and mad honey
poisoning, excluding acute coronary syndrome when the detected episodic LBBB has great prominence.
Human poisoning is rare, but there have been cases in Turkey where "mad honey
" - produced by bees visiting Rhododendron flowers - causes hallucinations, nausea and even death.
Rhododendron honey (mad honey
), produced from the rhododendron genus growing in the Black Sea region, contains a toxic substance, grayanotoxin (Qiang et al, 2011; Gunduz et al., 2007; Koca &Koca, 2007; Jansen et al, 2012).
We report herein a case of a patient with mad honey
intoxication mimicking acute non-ST segment elevation myocardial infarction and review the pathophysiology and diagnostic considerations.
Site of action of grayanotoxins in mad honey
This information immediately triggered Turk and colleagues to consider that their patients could be suffering from 'mad honey
poisoning is a well known condition in the Black Sea Region of Turkey.
The mad honey
is widely used as an alternative therapy for the treatment of gastrointestinal diseases such as gastritis, peptic ulcer and the reduction in the coronary artery disease (CAD) risk in Black Sea region of Turkey (1).
" made from the plant is said to cause cardiac arrest, paralysis and vomiting.
Physicians at the Karadeniz University School of Medicine in Trabzon, Turkey, report in the April 1 JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION that they have seen 16 cases of "mad honey
" poisoning in the last two years.