If there is an inflammatory reaction, two changes occur: first, more monocytes or
macrophages are recruited into the small intestine and second, there is a dramatic change in their gene expression.
To assess the potential of MPSE to modulate NO release in
macrophages, nitrite concentrations were detected in the culture supernatants of LPS-induced
macrophages in the absence or presence of MPSE.
Alternative activation of
macrophages: Mechanism and functions.
Case of tumoral melanosis with a massive infiltration of CD163+ and CD68+
macrophages. J Dermatol 2018;45:368-70.
After a muscle injury, one class of
macrophages shows up on the scene to clear the wreckage left behind, increase inflammation and stimulate other parts of the immune system.
The researchers observed a dose-dependent reduction in cell viability in
macrophage culture with ECL or ECVC.
These lesions eventually lead to the formation of granulomas (Flat and Moses, 1975) which are inflammatory nodular formations, mainly comprised by
macrophages or histiocytes of dense or loose connective tissue.
MAF specifically serves to activate
macrophages triggering an immunomodulatory effect, by linking to the vitamin D receptor (VDR).
At 13 weeks of age, peritoneal
macrophages and blood samples were collected, as previously described [3, 4, 9].
In the current study, we advance a computer vision approach to localize polarized
macrophages according to iron status in order to improve their quantification in USPIO-enhanced cellular imaging by MRI and histology.
There have been inconsistencies in the literature defining the role of
macrophages with respect to their contribution to osteogenesis around TCP bone particles.
Activation and Polarization of the Monocytic THP-1 Cells into M1 and M2
Macrophages. THP-1 monocytes were activated into
macrophages using 100 ng/mL phorbol-12-myristate-13-acetate (PMA) (Calbiochem, Temecula, CA, USA) for 24 h and then washed with medium.