macrolides


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Related to macrolides: clindamycin, Fluoroquinolones

mac·ro·lides

(mak'rō-līdz),
A class of antibiotics discovered in streptomycetes, characterized by molecules made up of large-ring lactones; for example, erythromycin; many inhibit protein biosynthesis.

mac·ro·lides

(mak'rō-līdz)
Class of antibiotics discovered in streptomycetes, e.g., erythromycin; many inhibit protein biosynthesis.
References in periodicals archive ?
Gastrointestinal disturbances, hepatic damages are the common side effects of macrolide antibiotics.
Macrolide resistance in Mycoplasma pneumoniae, Israel, 2010.
pneumoniae and fewer contraindications, macrolides have been the first choice for the clinical treatment of MPP (18,19).
- Watertown, Massachusetts-based antibiotic developer Macrolide Pharmaceuticals has been granted a CARB-X award of up to USD 6.8m to support the development of a novel fully synthetic, orally available macrolide antibiotic with Gram-negative activity, with the aim of treating serious infections including drug-resistant complicated urinary tract infections, the company said.
Fluoroquinolones or macrolides alone versus combined with B-lactams for adults with community-acquired pneumonia: systematic review and meta-analysis.
The aim of this study was to determine the presence of several VFs and the levels and molecular mechanisms of resistance to quinolones and macrolides in a series of Campylobacter spp.
Despite this fact, physician adherence to guideline-concordant antibiotic therapy remained infrequent as clinicians continued to use macrolides, especially azithromycin, as CAP monotherapy [18].
[16] 57 Undetermined Yes Reference Antimicrobial class (quinolone, Outcome macrolide, or both quinolone and macrolide) Koufakis et al.
this gene is responsible for an efflux mechanism which confers resistance to macrolides and type B streptogramins, but not to clindamycin.
Current guidelines recommend the latter two approaches, which has caused a widespread increase in the use of macrolides and fluoroquinolones--and in turn has increased antibiotic resistance.
Labro, "Anti-inflammatory activity of macrolides: a new therapeutic potential?" Journal of Antimicrobial Chemotherapy, vol.