Tilmicosin is a macrolide antibiotic
prepared by chemical alteration of desmycosin and interferes with bacterial protein synthesis (Yazar et al.
In 2001, Japanese scholar Okazaki  firstly extracted MP bacterial strain which has drug resistance to macrolide antibiotics
from the lower respiratory specimens of children patients with pneumonia and bronchitis.
pneumoniae had already received 14-membered macrolide antibiotics
for three days (median) before hospitalization and high fever persisted during hospitalization even with continuing use of macrolides.
Non antimicrobial activity: Apart from its conventional antibacterial action macrolide antibiotics
are known to have anti-inflammatory (6), immunomodulator acitivity (7 & 8) and antioxidant properties (9) and Erythromycin has been used clinically for its stimulatory effect on gastrointestinal motility.
The complete structure of the polyene macrolide antibiotic
* Vitamin C, macrolide antibiotics
, echinacea, ginseng Likely to be ineffective or harmful
are the first-line treatment for M.
Recombineering reveals a diverse collection of ribosomal proteins L4 and L22 that confer resistance to macrolide antibiotics
. J Mol Biol.
have antimicrobial and immunomodulary effects, and chronic administration has been associated with improvements in other Inflamtnatory lung conditions, such as cystic fibrosis.
(erythromycin, clarithromycin and azithromycin) are among the most widely prescribed antibiotics, with millions of prescriptions dispensed in Canada each year," said David Juurlink, Scientist at the Sunnybrook Research Institute and the Institute for Clinical Evaluative Sciences.
The well-documented benefits far outweigh the uncertain risks associated with pneumococcal resistance to macrolide antibiotics
The Company is the largest domestic manufacturer of macrolide antibiotics
, with a leading position for its intravenous infusion solution products in high-end hospital market.The Company boasts of its robust brand strength including "Lijunsha", a "Famous Trademark" in China and one of the "Ten Favourite Trademarks" which took over approximately 66% market share in 2008.