First group of macrocyclic compounds are crown ethers, which contain oxygen, sulfur, and nitrogen as donor atoms.
It is found that sulfur atom affects the rigidity of the macrocycles and diastereotopicity of nuclei in the ring of these series of macrocyclic compounds .
HitGen's DELs contain nearly 400m novel, diverse, drug-like small molecule and macrocyclic compounds
Calixarenes are an important class of macrocyclic compounds
in supramolecular chemistry, which offer an emerging base/platform for synthesizing new and efficient ligands.
8 December 2009 - US biopharmaceutical company Tranzyme Pharma said today it has inked a strategic collaboration agreement with Bristol-Myers Squibb Company (NYSE: BMY) to discover, develop and commercialise novel macrocyclic compounds
directed against targets of interest to Bristol-Myers Squibb.