macrocycle

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macrocycle

A several-month period of mezocycles of vigourous training followed by short periods of lighter training, as by an athlete preparing for a competitive sports event.
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Tranzyme is also pursuing development of several other macrocyclic compounds emanating from its internal research program, including a second generation, oral ghrelin agonist, TZP-102, currently in Phase 2 trials, and two preclinical compounds, TZP-201 for severe diarrhea indications such as chemotherapy-induced diarrhea, and TZP-301, a ghrelin antagonist, for metabolic disorders.
Patent and Trademark Office (USPTO) for two patent applications entitled "Macrocyclic Modulators of the Ghrelin Receptor" and "Spatially-Defined Macrocyclic Compounds Useful for Drug Discovery".
amp; SHERBROOKE, Quebec -- Tranzyme Pharma, a leading biopharmaceutical company developing novel mechanism-based therapeutics for the treatment of gastrointestinal (GI) and metabolic disorders, announced today the issuance of a European patent (EP 1 218 403) entitled "Combinatorial Synthesis of Libraries of Macrocyclic Compounds Useful in Drug Discovery.
Patent and Trademark Office (USPTO) for its patent application entitled "Combinatorial Synthesis of Libraries of Macrocyclic Compounds.