macrocycle

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macrocycle

A several-month period of mezocycles of vigourous training followed by short periods of lighter training, as by an athlete preparing for a competitive sports event.
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References in periodicals archive ?
All of Tranzyme's product candidates have been discovered using its proprietary drug discovery (chemistry) technology, MATCH[TM], which enables the construction of synthetic libraries of drug-like, macrocyclic compounds in a predictable and efficient manner.
Tranzyme Pharma today announced that it has entered into a strategic collaboration agreement with Bristol-Myers Squibb Company (NYSE: BMY) to discover, develop and commercialize novel macrocyclic compounds directed against targets of interest to Bristol-Myers Squibb.
Originating from its proprietary library of conformationally-defined macrocyclic compounds, Tranzyme's internal R&D efforts discovered a potent and selective ghrelin agonist, TZP-101.
Patent and Trademark Office (USPTO) for two patent applications entitled "Macrocyclic Modulators of the Ghrelin Receptor" and "Spatially-Defined Macrocyclic Compounds Useful for Drug Discovery".
amp; SHERBROOKE, Quebec -- Tranzyme Pharma, a leading biopharmaceutical company developing novel mechanism-based therapeutics for the treatment of gastrointestinal (GI) and metabolic disorders, announced today the issuance of a European patent (EP 1 218 403) entitled "Combinatorial Synthesis of Libraries of Macrocyclic Compounds Useful in Drug Discovery.
Patent and Trademark Office (USPTO) for its patent application entitled "Combinatorial Synthesis of Libraries of Macrocyclic Compounds.