machine perfusion


Also found in: Dictionary, Thesaurus, Encyclopedia, Wikipedia.

machine perfusion

In organ transplantation, the infusion of donated organs with fluids that supply necessary nutrients and wash away metabolic by-products. It is used to improve the viability of the organs before and after they are transplanted into recipients.
See also: perfusion
References in periodicals archive ?
Hypothermic machine perfusion of kidneys retrieved from standard and high-risk donors.
Karimian et al., "Hypothermic oxygenated machine perfusion prevents arteriolonecrosis of the peribiliary plexus in pig livers donated after circulatory death," PLoS ONE, vol.
Brassil, "Islet isolation from juvenile porcine pancreas after 24-h hypothermic machine perfusion preservation," Cell Transplantation, vol.
Roberts et al., "Cold machine perfusion versus static cold storage of kidneys donated after cardiac death: a UK multicenter randomized controlled trial, " American Journal of Transplantation, vol.
tGST activity in kidney perfusate samples, collected hourly during machine perfusion and stored at -20 [degree]C, was measured with an automated (Roche[R] Cobas Mira) spectrophotometric method, described by Habig and Jakoby (11), based on the conjugation of chlorodinitrobenzene at 25 [degree]C with glutathione to form glutathione Sdinitrobenzene, with the absorbance of the product measured at 340 nm.
Hypothermic machine perfusion in DCD kidney transplantation: A single center experience.
Studies that did not include DCD livers and those that focused only on hypothermic or subnormothermic machine perfusion were excluded.
Ozer et al., "Subnormothermic machine perfusion for ex vivo preservation and recovery of the human liver for transplantation," American Journal of Transplantation, vol.
To mitigate against heightened preservation injury in DCD kidneys, hypothermic pulsatile machine perfusion preservation is utilized.
70 out of 336 kidney recipients in the machine perfusion group developed delayed graft function (DGF) compared to 89 out of 336 in the cold storage group (adjusted odds ratio 0.57; P=0.01)
TransMedics offers portable ex-vivo machine perfusion and assessment of donor organs for transplantation.
The clinical trial will compare outcomes in pairs of patients who receive contralateral pairs of donor kidneys, one preserved by machine perfusion and the other by static storage, with left or right kidneys randomly assigned, the steering committee said in a press release.
Full browser ?