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Related to Mach: Ernst Mach, Mach kernel


Ernst, scientist in Hapsburg Empire, 1838-1916. See: Mach band, Mach number.
Farlex Partner Medical Dictionary © Farlex 2012


A gene on chromosome 2q33-q34 that encodes a protein belonging to the cysteine-aspartic acid protease (caspase) family which, once activated by proteolytic processing, plays a central role in the execution phase of cell apoptosis, as well as various stages of embryological development. CASP8 is an initiator-type caspase, which is activated by, and interacts with, upstream adaptor molecules through CARD and DED protein–protein interaction domains; it is involved in the programmed cell death induced by Fas and various apoptotic stimuli. It is highly expressed in peripheral blood leukocytes and in the spleen, thymus and liver.

Molecular pathology
CASP8 has been detected in the insoluble fraction of affected brain regions in Huntington disease, suggesting a role in neurodegenerative diseases.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.
References in periodicals archive ?
Ford initially planned to call this electric vehicle (EV) the Mach 1.
MACH was recently sold out in just five minutes in the IEO on the IDAX exchange, and this collaboration with the global blockchain Mainet Ontology has given a big boost to MACH Platform and MACH Coin's plan to make inroads into the world.
Since BC is ultimately related to Cd, when you calculate a BC it is only for one specific Mach number.
Running alongside MACH are the biennial co-located events; Plant & Asset Management, Drives & Controls, Smart Industry Expo, Fluid Power & Systems, and Air-Tech Exhibitions in Halls 8, 9 and 10 (
Starhome Mach enables seamless and secure roaming and IoT connectivity.
While not citing Ricks and Veneziano (1988) or discussing the findings of this earlier study, Ricks and Fraedrich (1999) use the same data reported by Ricks and Veneziano (1988); they breakdown the data into low and high Mach's for B2B versus B2C salespersons.
The plan was "overwhelmingly supported'' by creditors and owners, allowing Mach Gen to get through bankruptcy in about 40 days, company lawyer Michael E.
An artist of worldwide reputation, Methil-born David Mach is best known for large scale innovative sculptural installations.
According to an informed source, the European Commission's green light for this transaction, announced in July 2012, will depend on Syniverse agreeing to sell whole segments of Mach's business and part of its customer base.
MACH Energy, a provider of energy management software service solutions for the commercial real estate marketplace, has signed a contract with Cassidy Turley, a commercial real estate services provider in the United States.
The Rite of Spring, CBSO and Julia Mach Symphony Hall So much could have gone wrong with the mind-blowing technology: several stereoscopic cameras focusing from various angles upon one lone dancer in the corner of the stage; computer software which instantly transmuted the live images and projected them onto a huge screen behind an equally huge orchestra, cramped on a necessarily reduced platform; and all kinds of other gremlins could have crept in.
Hyderabad, March 31 -- MACH, the leading provider of hub-based mobile communication solutions, today announces the appointment of Richard Grohol to the position of Chief Commercial Officer.