MAB

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MAB

Abbreviation for monoclonal antibody.

MAB

abbreviation for monoclonal antibody.

monoclonal antibody

Diagnostics
Mabs are used in diagnostics by radioactively labelling them to target malignant cells, detect metastases and screen body fluids for microorganisms, or measure levels of circulating hormones.

Fringe oncology
Alternative healthcare providers may include therapeutic Mabs as a part of treatment.

Immunology
A highly specific antibody formed by a clone of B lymphocytes, either naturally (e.g., in cold haemagglutinin) or produced synthetically by fusing an immortal cell (mouse myeloma) to a cell producing an antibody against a desired antigen.

Oncology
Mabs are increasingly used in cancer management as they directly inhibit the growth of certain tumours, can be chemically bound to toxins that are lethal to malignant cells, stimulate the complement system in destroying malignant cells, can be used to purge the BM of malignant cells, and form the basis for vaccines and drug delivery systems.
 
Adverse effects
Allergic reactions, fevers, chills, hypotension, liver and kidney problems.
 
Pathology
Mabs are used in pathology to differentiate tumour subtypes with batteries of Mabs raised against intermediate filaments or membrane antigens.

MAB

Monoclonal antibody, Monoclonal antibodies

mAb

abbrev. MONOCLONAL ANTIBODY.

MAb

monoclonal antibody.