KAT8

(redirected from MYST1)

KAT8

A gene on chromosome 16p11.2 that encodes a histone acetyltransferase which may be involved in transcriptional activation.
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References in periodicals archive ?
In addition, MYST3 was reciprocally upregulated by LPS, while MYST1, MYST2, and MYST5 were only marginally affected.
MYST1 mRNA was not significantly regulated by LPS treatment (Figure 3(b)).
Acetylated H4K16 by MYST1 protects UROtsa cells from arsenic toxicity and is decreased following chronic arsenic exposure.
Moreover, knockdown of MYST1, the gene responsible for H4K16 acetylation, resulted in increased cytotoxicity from arsenical exposure in human bladder epithelial cells, suggesting that H4K16 acetylation may be important for resistance to arsenic-induced toxicity.