MYOD1

A gene on chromosome 11p15.4 that regulates myogenesis by encoding MyoD1, a nuclear phosphoprotein with partial homology to the myc family of oncoproteins, which binds to the enhancer sequences of the muscle-specific creatine phosphokinase gene, inhibiting DNA synthesis and cell proliferation. MyoD1 belongs to the basic helix-loop-helix (bHLH) transcription factor family and the myogenic factors subfamily. It regulates muscle cell differentiation by inducing cell cycle arrest, a prerequisite for myogenesis, and is involved in muscle regeneration.

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Keratin MnF, desmin, CD34, podoplanin (D2-40), S100, H-caldesmon, myogenin, MyoD1, CD68, p63, human herpes virus 8, and factor XIII are typically negative (Figures 3 through 6).

Pseudomyogenic Hemangioendothelioma

Thigh meat% and heart% were found to be significantly higher in male Japanese quails treated by FR1 than others showing an aesthetic effect of post-hatch early feeding.This might be due to increased expression of myogenic regulatory factors (MYOD1) in birds with post-hatch immediate access to feed which possibly had enhanced the satellite cells differentiation and led to muscle hypertrophy via myonuclear accretion and protein synthesis as observed by Powell et al.

POST HATCH PERFORMANCE OF MEAT TYPE JAPANESE QUAIL INFLUENCED BY TIME OF OFFERING FEED AND AMBIENT ENVIRONMENT

The tumor did not stain with P16, CEA, beta HCG and P63, desmin, MyoD1, CD10, caldesmon, and cyclinD1.

Uterine giant cell carcinoma: a case report and review of the literature/Uterin dev hucreli karsinom: olgu sunumu ve literatur sunumu

Markers of muscular differentiation (desmin, myogenin, MyoD1, and smooth-muscle actin) and melanocytic markers (S100-protein, HMB-45, and melan-A) were negative.

Pseudomyogenic hemangioendothelioma: a little-known tumor

Furthermore, LPS was also shown to decrease expression of myogenic factor, including myod1 and myogenin (MyoD1: t = 4.039, P < 0.05 and myogenin: t = 3.300, P < 0.01), but dandelion extract was shown to against this effect of LPS (MyoD1: t = −3.160, P < 0.05 and myogenin: t = −3.207, P < 0.01).

Effects of Dandelion Extract on the Proliferation of Rat Skeletal Muscle Cells and the Inhibition of a Lipopolysaccharide-Induced Inflammatory Reaction

(1991) Characterization of a genomic clone covering the structural mouse MyoD1 gene and its promoter region.

Skeletal Muscle Estrogen Receptor Activation in Response to Eccentric Exercise Up-Regulates Myogenic-Related Gene Expression Independent of Differing Serum Estradiol Levels Occurring during the Human Menstrual Cycle

It is important to note that the tumour stained negative for myogenin, myoD1, des-min, S-100, nuclear beta-catenin, and MUC4.

Case: Pediatric paratesticular soft tissue perineurinoma--A rare entity

Li, "Stepwise acetyltransferase association and histone acetylation at the Myod1 locus during myogenic differentiation," Scientific Reports, vol.

Epigenetic Contribution of High-Mobility Group A Proteins to Stem Cell Properties

Promoter hypermethylation of some other genes like MYOD1, CALCA, hTERT, and RASSF1A can also be detected in serum samples of cervical cancer patients and are related to lymph node metastasis and FIGO stage [42, 43].

The Progress of Methylation Regulation in Gene Expression of Cervical Cancer

NCAM: neural cell adhesion molecule; MAP2: microtubule-associated protein 2; NeuN: neuron-specific nuclear protein; Fit-I: VEGF receptor 1; KDR: VEGF receptor 2; CD34: cluster of differentiation 34; ICAM-I: intercellular cell adhesion molecule-1; vWF: von Willebrand factor, DSP: dentin sialoprotein, DMP1: dentin matrix acidic phosphoprotein 1, BSP: bone sialoprotein, OCN: osteocalcin, MyoD1: myoblast determination protein 1; MHC: major histocompatibility complex; PCR: polymerase chain reaction; FC: flow cytometry; ICC: immunocytochemical.

Potential Roles of Dental Pulp Stem Cells in Neural Regeneration and Repair

Other genetic alterations include the NCOA2 gene fusion, which is common in congenital cases, and the MYOD1 gene mutation, which tends to occur in older children and adults.

Congenital Rhabdomyosarcoma Presenting as a Neck Mass at Birth

Hosli et al., "Inv(11)(p13p15) and Myf-3(MyoD1) in a malignant extrarenal rhabdoid tumor of a premature newborn," Pediatric Research, vol.