MYO1C


Also found in: Dictionary, Encyclopedia.

MYO1C

A gene on chromosome 17p13.3 that encodes an actin-based molecular motor of the unconventional myosin protein family, the nuclear isoform of which associates with RNA polymerase I and II and functions in transcription initiation.
References in periodicals archive ?
The mutation (called R156W), was first identified in an individual suffering from cochlear hearing loss, and it affects the way the myo1c protein interacts with proteins known as actin filaments, another crucial component of the sensory apparatus of the inner ear.
Though the cochlear cell myo1c defects are associated with hearing loss, how this mutation causes the disease is still a mystery.