MYH1

MYH1

A gene on chromosome 17p13.1 that encodes a heavy chain of myosin and is thus involved in cytokinesis, cell shape and specialised functions—e.g., secretion and capping.
References in periodicals archive ?
An integrated in silico approach for functional and structural impact of non- synonymous SNPs in the MYH1 gene in Jeju Native Pigs.
Predesigned primers for human PPARGC-1 (Hs01016719_m1), D2DR (dopamine 2 receptor, Hs00241436_m1), VEGF (vascular endothelial growth factor, Hs00900055_m1), MyH1 (myosin heavy chain 1, Hs00428600_m1), MyH2 (myosin heavy chain 2, Hs00430042_m1), Desmin (Hs00157258_m1), [alpha]-actinin (Hs00998100_m1), COXIV (cytochrome c oxidase subunit 4,Hs00971639_m1), vWf (Mm00550375_m1), TNF-[alpha] (tumor necrosis factor alpha, Mm00443258_m1), and ACHE (acetyl choline esterase, Hs00241307_m1) were purchased from Life Technologies.
Myosin genes couldbe divided into several classifications [53], such as myosin heavy chain 1 (MYH1), myosin light chain 3 (MYL3), and myosin binding protein C2 (MYBPC2).
TGF-[beta] inhibitors (SB431542 or A83-01) significantly facilitated myotube fusion and maturation, as demonstrated by MHC protein levels (MYH1 and MYH8) and sarcomere formation.
Critical myogenic genes involved in myotube differentiation including Pax7, myogenin (MyoG), myosin heavy chain 1 (MYH1), hairy/enhancer-of-split related with YRPW motif protein 1 (Hey1), DNA-binding protein inhibitor ID1 (ID1), and activin A receptor type I (ACVR1) were precipitously downregulated in MyoD KO QM7#4 cells (Table 2).