MVK


Also found in: Acronyms.

MVK

A gene on chromosome 12q24 that encodes mevalonate kinase, which plays a regulatory role in cholesterol biosynthesis.

Molecular pathology
Defects in MVK cause mevalonic aciduria and hyperimmunoglobulinaemia D, and periodic fever syndrome.
References in periodicals archive ?
A novel MVK splicing mutation, designated as IVS4+1G>A (NM_000431.
Many mutations in MVK , PMVK , MVD , and FDPS genes have been detected in patients with PK.
A novel MVK splicing mutation (IVS4+1G>A) has expanded the database of MVK mutations and may help elucidate the pathogenesis of PK.
Hyperimmunoglobulin D syndrome develops as a result of mutations of the gene coding for the enzyme MVK, which plays a role in cholesterol and isoprenoid synthesis.
There are 65 different mutations found on the MVK gene.
This makes MVK a way for people to keep their PINs and passwords safe and in one place.
MVK also features a flexible vault for personal data.
12] Our case was also evaluated for the most common two mutations (V377I, I268T) of the MVK gene and was found negative.
1] Research efforts are still ongoing to create a connection between elevated IgD levels and mutations in the MVK gene.
Project name : Ploughing before planting and Inter ploughing in the plantation site MVK 1 closed mine area MVK 1 Kothapally Air shaft area and MVK 5 Exploration Magazine area and fan house