MVE virus is not only found in the Murray Valley region, but it is also endemic in northern Australia and probably in Papua New Guinea.
The primary vertebrate hosts of MVE virus are water birds, including herons and cormorants.
MVE virus can cause a range of disease in humans, from subclinical infection without any symptoms; to mild illness characterized by fever, headache, myalgia, arthralgia, nausea, and vomiting; to severe illness involving the central nervous system.
Peptide 0020, the fourth strong binder, was conserved in West Nile and Kunjin (100%), JE virus, MVE virus, and dengue (90%).
WN virus 0015 was conserved in WN virus, Kunjin (100%), JE virus (90%), MVE virus (80%), SLE virus (90%), and dengue (80%).