MAP3K12

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MAP3K12

An oncogene on chromosome 12q13 that encodes a MAPK kinase kinase belonging to a protein kinase signal transduction cascade. MAP3K12 may activate the JNK/SAPK pathway; it is highly expressed in brain and kidney.

Each mitogen-activated protein kinase (MAPK) pathway is a conserved cascade of three protein kinases: an activated MAPK kinase kinase (MAPKKK) phosphorylates and activates a specific MAPK kinase (MAPKK), which in turn activates a specific MAPK.
References in periodicals archive ?
MUK eleven is part of the Myeloma UK Clinical Trial Network, a portfolio of early stage trials coordinated by the Clinical Trials Research Unit at the University of Leeds, focused on testing and speeding up access to promising new treatments for patients.
Its objective is to help qualified individuals and families who are living in Lei Muk Shue (II) Estate by recycling of good quality prepackaged products.
Today, however, individuals who process salt here have to contribute 5 muk per boiling process to the kas lokasi (village fund) and another 5 muk per boiling to the bebpat pulu' sidang (church tithe).
Muk and I went to gather silverstools, shiny gray mushrooms that tasted like fish, and she told me a story, which, much later, I realized revealed her jealousy.
Its citation named her as Ng Muk Kah - an out-andout surprise to many, to whom she was, and always will be, Jenny.
One of the top aides to North Korean leader Kim Jong Il, Yon Hyong Muk, died of an unspecified illness Saturday, the North's official Korean Central News Agency reported Sunday.
Some of the writers will be familiar to anyone who has begun to read in the field: Jack Davis, Lisa Bellear, and John Muk Muk Burke are already established, and their selections here are solid but not surprising.
Fullerton); "A Content Analysis of Print Advertising Appeals in Times of Crisis" (Alexander Muk); "Advertising Theory Beyond the Context of Advertising: Taylor's Six-Segment Message Strategy Wheel Offers an Integrated Model of Political Behavior" (Anne Cunningham and Eric Jenner); "Understanding Celebrity Endorsers in Cross-Cultural Contexts: An Exploratory Analysis of South Korean and U.S.
A study found that children were more likely to remember names like pikachu, metapod, muk and wigglytuff than mouse, otter, beetle and oak tree.
The aircraft was operated by Muk Air, a Danish carrier.
'There's no room for 'Muk Muka' and 'Noora Kushti' in the country anymore,' he remarked.