MUC7

A gene on chromosome 4q13.3 which encodes a small salivary mucin, thought to facilitate clearance of bacteria in the mouth and help mastication, speech and swallowing.

References in periodicals archive ?

Based on the structure and function of a molecule, mucin is subdivided into 3 categories: membrane-bound mucins (MUC1, MUC3 MUC4, MUC12, MUC16, MUC17), gel-forming (secreted) mucins (MUC2, MUC5AC, MUC5B, MUC6, MUC19), and soluble mucin (MUC7).

Significance of mucin expression in pancreatic intraepithelial neoplasia (PanIN)--precursor lesions of pancreatic ductal adenocarcinoma (PDAC)

Salivary glycoconjugates such as mucins (MUC1, MUC4, MUC5B, MUC7, and MUC19), proline-rich glycoproteins (PRGs), and kallikrein may also ensure the appropriate hydration of the oral mucosa and maintain the proper pH of the stimulated and nonstimulated saliva [8, 9].

Lysosomal Exoglycosidase Profile and Secretory Function in the Salivary Glands of Rats with Streptozotocin-Induced Diabetes

DAMP TLR Refs (i) Biglycan and decorin are degraded TLR2 and by saliva from NOD.B10 mice TLR4 [95] (ii) Versican is increased in SGEC lines TLR2/6 [108] from SS patients heterodimer (i) Fibronectin is dysregulated in salivary [109] tissue from SS mice and upregulated in [110] saliva from SS patients [95] (ii) Calprotectin (S100A8/A9) levels are TLR4 [111] elevated in sera, salivary tissue, and [112] saliva of pSS patients [113] (iii) MUC5B and MUC7 are mislocalized [114] in the ECM of pSS patients [115] (i) Long interspersed nuclear element 1 [116] (LINE-1) is increased in MSG tissue TLR 7/8 [117] from SS patients

Current and Emerging Evidence for Toll-Like Receptor Activation in Sjogren's Syndrome

Higher levels of salivary MUC5B and MUC7 in individuals with gastric diseases who harbor Helicobacter pylori .

Saliva: Newer avenues in the era of molecular biology, diagnostic and prognostic application

The MUC7 gene variant produces the protein that makes spit slimy and holds tight to microbes, preventing them from entering your body through your mouth.

Prehistoric Sex: Why Some People Have More Neanderthal DNA

5-HTT intron 2 and MUC7 variable number of tandem repeats polymorphisms in a Venezuelan population with asthma or COPD.

Polimorfismos de numero variable de repeticiones en tandem del intron 2 de 5-HTT y MUC 7 en pacientes venezolanos con asma o EPOC

Two-hybrid analysis of human salivary mucin MUC7 interactions.

Histochemical Characterization of Convict Cichlid (Amatitlania nigrofasciata) Intestinal Goblet Cells

Relation extraction task was formally put forward in MUC7 by Message Understanding Conference (MUC) supported by Defense Advanced Research Projects committee (DARPA) in 1998.

Support vector machine with ensemble tree kernel for relation extraction

Over expression, aberrant intracellular localization, and changes in glycosylation of MUC1 and MUC7 are often reported in tumors of colon, breast, ovarian, lung, and pancreatic origin [24, 48].

First comprehensive in silico analysis of the functional and structural consequences of SNPs in human GalNAc-T1 gene

Human breast tissue was used as a control for MUC1; human colon for MUC2, 3 and 4; human gastric mucosa for MUC5AC and 6; human bronchial mucosa for MUC5B, and human submandibular salivary gland for MUC7. Negative controls consisted of sections from normal human liver, as it does not express any of these mucin genes.

Mucin gene expression in reflux laryngeal mucosa: histological and in situ hybridization observations

Sheehan, "Identification of salivary mucin MUC7 binding proteins from Streptococcus gordonii," BMC Microbiology, vol.

Exploiting unique structural and functional properties of malarial glycolytic enzymes for antimalarial drug development

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