MUC16

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MUC16

A gene on chromosome 19p13.2 which encodes a protein that provides a protective lubricating barrier against particles and infectious agents at mucosal surfaces. It is more commonly known as CA125, and is a highly characteristic marker of ovarian carcinomas.
References in periodicals archive ?
This study analysed two versions of the armored CAR in mouse models one against CD-19 positive targets, and the second against MUC-16 positive targets.
CD-19 antigens are found on B-Cell malignancies, while MUC-16 antigens are found on some ovarian and pancreatic cancers.
Haab's) identification of variants of MUC-1, MUC-5AC, and MUC-16 (genes) within the cyst fluid of pre-malignant lesions is exciting as our current ability to non-operatively define these lesions is limited.