MT5-MMP | definition of MT5-MMP by Medical dictionary
MMP24 (redirected from MT5-MMP)
MMP24 A gene on chromosome 20q11.2 that encodes membrane-type matrix metalloproteinase 24. Unlike other matrix metalloproteinases, which are secreted as inactive proproteins and activated when cleaved by extracellular proteinases, MMP24 is a transmembrane protein. It activates progelatinase A and may also cleave proteoglycans (e.g., dermatan and chondroitin sulfates) and partially cleave fibronectin.
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References in periodicals archive
Besides MMP-2 and MMP-3, putative NLSs in the sequences of MMP-1, MMP-8, MMP-10, MMP-13, MMP-19, MMP20, and MMP-23 and MT1-MMP, MT3-MMP, MT4-MMP, and MT5-MMP
were also detected , which suggests that nuclear entry may be a feature of many MMPs.
activates pro-MMP2, exhibiting a strong expression in brain tumors .
Grupo Colagenases MMP Nome enzimatico MMP-1 Colagenase intersticial MMP-8 Neutrofilo colagenase MMP-13 Colagenase-3 Gelatinases MMP-2 Gelatinase A MMP-9 Gelatinase B Estromalisinas MMP-3 Estromalisina-1 MMP-10 Estromalisina-2 MMP-11 Estromalisina-3 MMPs tipo MMP-14 MT1-MMP membrana MMP-16 MT3-MMP MMP-17 MT4-MMP MMP-24 MT5-MMP
MMP-25 MT6-MMP Outras MMP-7 Matrilisina MMP-26 Matrilisina-2 MMP-12 Macrofago metaloelastase