MSTN


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MSTN

A gene on chromosome 2q32.2 that encodes myostatin, a member of the bone morphogenetic protein family, which regulates cell growth and differentiation in both embryonic and adult bone and cartilage. Myostatin appears to downregulate skeletal muscle growth.
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In this study, we designed two adjacent (+7 bp offset, Figure 1B) but opposite single-strand breaks in chicken MSTN gene for Cas9-D10A nickase.
Therefore, in this study we used 17-week-old Sansui ducks to study the association of single nucleotide polymorphisms (SNPs) in MSTN exon and slaughter traits.
The ability of saActRIIB-2a-ECD to inhibit MSTN and activin A activities in vitro was measured using the pGL3-[(CAGA).
To investigate the diversity within the population or MSTN gene diversity in the study population estimating the observed heterozygosis (H_0) and expected heterozygosis (H_e) found that the results are presented in Table 6 .
Briefly, primary fibroblast cells and MSTN targeted cells were seeded at 2,000 cells per well in 96-well plates and counted for 6 days continuously at 24, 48, 72, 96, 120 h incubation by addition of 10 [micro]L CCK-8 reagent to each well.
The TALENs were designed to target the sequence of exon 2 in the sheep MSTN gene.
A sequence polymorphism in MSTN predicts sprinting ability and racing stamina in Thoroughbred horses.
A polymerase chain reaction (PCR) primer pair (Forward 5'-GAC TTGTGACAGACAGGGTTT-3' and Reverse 5'-AATCT TTATGGCTTCTATTCTTG-3') was newly designed in this study to amplify the 5'regulatory region according to the reference sequence of rabbit MSTN (GenBank accession number GU938461.
The association of muscular hypertrophy with ovine MSTN variation was first reported in Belgian Texel sheep (Clop et al.
The main emphasis of our research has shifted to analyze the SNPs in the regulatory region (putative promoter and UTRs) because they are most likely to influence the meat traits by modulating the level of MSTN expression.
ABSTRACT : The objective of this study was to assess the association of polymorphisms in MSTN and MYF5 genes with growth traits in three Chinese cattle breeds.