STK24

(redirected from MST3)

STK24

A gene on chromosome 13q31.2-q32.3 that encodes a serine/threonine-protein kinase which acts on serine and threonine residues and promotes apoptosis in response to stress stimuli and caspase activation. STK24 mediates oxidative-stress-induced cell death by phosphorylating JNK1-JNK2 (MAPK8 and MAPK9) and p38 (MAPK11, MAPK12, MAPK13 and MAPK14) during oxidative stress. It regulates cellular migration by altering PTPN12 activity and PXN phosphorylation, and it may be a key regulator of axon regeneration in the optic and radial nerves.
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The MST3 Son of Time Chronos Joyride Special Edition sports a 45-mm steel case with black Italian leather strap, black stitching and sunray gray dial.
The MST kinase family, which is related to the Hippo kinase in Drosophila melanogaster, consists of five related proteins: STK3 (also known as MST2), STK4 (also known as MST1), STK24 (also known as MST3), STK25 (also known as YSK1), and STK26 (also known as MST4) [19].