CFTR(redirected from MRP7)
Also found in: Dictionary, Thesaurus.
CFTRA gene on chromosome 7q31.2 that encodes cystic fibrosis transmembrane conductance regulator, a protein of the MRP subfamily of the superfamily of ATP-binding cassette (ABC) transporters, which transport various molecules across extra- and intracellular membranes and many of which are involved in multidrug resistance. CFTR functions as a chloride channel and controls the regulation of other transport pathways.
CFTR mutations cause cystic fibrosis and bilateral aplasia of the vas deferens.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.
Abbreviation for cystic fibrosis transmembrane regulator.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012