MRHU may be caused by the transport of biological molecules (bacterial metabolites= haemagglutinine, flocculine) through BNT (Biological nano-tubes)=fimbriae= pili and were evaluated at different MRHA and Sero-typing, caused by viable cell and by the isolated fimbriae=pili=BNT.
The unique process incorporates an active agent that inhibits the growth of potentially lethal bacteria, including antibiotic-resistant superbugs such as the deadly 'golden staph' or MRHA. As such, it is highly effective when used on products likely to be located in areas subject to contamination.
Haemagglutination inhibited in presence of D-mannose was labeled as mannose sensitive haemagglutination (MSHA); indicating type1 fimbriae, if agglutination occurred even in presence of D-mannose, it was called mannose resistant haemagglutination (MRHA); indicating presence of P fimbriae (Uma et al., 2013).
The focus of these articles is an interpretation and critique of the second version of the MRHA data integrity guidance for laboratories working to European Union GMP regulations, such as analytical development in R&D and quality control in pharmaceutical manufacturing.