MRC2

MRC2

A gene on chromosome 17q23.2 that encodes a C-type lectin domain protein which may play a role as a lectin receptor by internalising glycosylated ligands from the extracellular space for release in an endosomal compartment via clathrin-mediated endocytosis. Mannose receptor C-type 2 may play roles in plasminogen activation by controlling the extracellular level of PLAUR/PLAU; in cellular uptake and remodelling, and in degradation of extracellular collagen matrices; in cancer and chronic tissue-destructive diseases acting on collagen turnover; and may participate in extracellular matrix remodelling in concert with matrix metalloproteinases.
References in periodicals archive ?
Differently, beside sugar metabolism, several DF factors appeared to have a role in ossification and/or bone metabolism (HNRNPC, MRC2, RBMX, RRBP1, TNC, and TWSG1, Figure 3).
Of note, several proteins, which are involved in bone metabolism and ossification (HNRNPC, MRC2, RBMX, RRBP1, TNC, and TWSG1), were also highlighted.
The expression of the M2 microglia marker MRC2 and of IL-10 and IL-1[beta] was increased in the prefrontal cortex of olfactory bulbectomized-SNL rats, which indicated that chronic minocycline administration had an effect on altering M1/M2 microglia markers [50].
The human ASM-MRC2 was cloned by RTPCR using primers designed from cDNA of MRC2 and mRNA isolated from human bronchial ASM cells.
Investigation to determine possible association between MRC2 SNPs and asthma is underway.
Delivery will require to be made to the Police Scotland Logistics Department, MRC2, 91 Meiklewood Road, Glasgow, G51 4DU, or other locations as may be specified from time to time as and when required throughout the Contract period.
Multiple ICC markers, including galectin-3 (GAL-3), HBME-1, CK19, CXCR4, CD44, HMGA2, MRC2, SFN, and cyclins D1 and D3, have been investigated on cell block materials individually, and all have demonstrated some value in distinguishing benign from malignant lesions.
mrc2.dct (MRC Database) For each Text entry, Repeat For each word Get nlet, conc,aoa, nphon, nsyl, fam, kffreq,kfncats,kfnsamp, tlfreq, brfreq, meanp, meanc, imag Calculate avg value of each field for the conversation Output: File Containing MRC Field values for all entries in dataset Testing Set Preparation:
There are two types of MR in humans each encoded by its own gene, (i) mannose receptor C type 1 (MRC1) and (ii) mannose receptor C type 2 (MRC2).
Metanalysis of 15,693 elderly patients with Systolic Hypertension Metanalysis of Systolic Hypertension Total Patients Average Age SHEP 4,736 72 SYST-EUR 4,695 70 SYST-CHINA 2,394 67 EWPHE 172 73 HEP 349 70 STOP 268 76 MRC1 428 62 MRC2 2,651 70 Table 4.
Contract Award Notice: Delivery of Pre Printed Notebooks will require to be made to the Police Scotland Logistics Department, MRC2, 91 Meiklewood Road, Glasgow, G51 4DU, or other locations as may be specified from time to time as and when required throughout the Contract period.