IGF2R

(redirected from MPR1)

IGF2R

A gene on chromosome 6q26 that encodes a receptor for both insulin-like growth factor 2 (IGF2) and mannose 6-phosphate (M6P). IGF2R plays a role in intracellular trafficking of lysosomal enzymes, activating transforming growth factor beta, IGF2 degradation and regulating T-cell coactivation by binding DPP4.
References in periodicals archive ?
P-glycoprotein (P-gp) and multidrug resistance-associated protein 1 (MPR1) are induced by arsenic trioxide ([As.sub.2][O.sub.3]), but are not the main mechanism of [As.sub.2][O.sub.3]-resistance in acute promyelocytic leukemia cells.
Creatinine was measured by enzymatic colorimetric test (CREA, MPR1, creatinine PAP; Boehringer Mannheim, Mannheim, Germany), and urinary creatinine levels were used to estimate urinary dilution.