KAT7

(redirected from MOZ, YBF2/SAS3, SAS2 and TIP60 protein 2)

KAT7

A gene on chromosome 17q21.32 that encodes a component of the HBO1 complex which is responsible for the bulk of histone H4 acetylation. KAT7 specifically represses AR-mediated transcription; it may regulate DNA replication by chromatin acetylation and act as a coactivator of TP53-dependent transcription.