MOC 31

MOC 31

A mouse monoclonal antibody that recognises a 38-kD membrane glycoprotein present in epithelial cells (epithelial cell-adhesion molecule), which in humans is encoded by EPCAM. The MOC-31 epitope is similar to epithelial membrane antigen (EMA) and expressed in a wide array of carcinomas, but not in lymphomas, melanomas, mesotheliomas or neuroblastomas. It is absent in hepatocellular carcinoma, but present in most other carcinomas including cholangiocarcinoma.
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