DYRK1A

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DYRK1A

A gene on chromosome 21q22.13 that encodes a member of the dual-specificity tyrosine-phosphorylation-regulated kinase (DYRK) family, which catalyses its autophosphorylation on serine/threonine and tyrosine residues. DYRK1A may play a key role in a signalling pathway that regulates cell proliferation and may be involved in brain development. 

Molecular pathology
DYRK1A is a candidate gene for learning defects associated with Down syndrome.
References in periodicals archive ?
These recent regulatory documents of the central bank also relate to the recommendation on managing credit risk already in force and to the provisions of the recently amended MNB Decree 39/2016.
Fergus Laird, head of investment at Naylors said: "The shops we have acquired for MNB Properties provide excellent prospects for long-term income while offering a number of opportunities to enhance values.
But it's the reason for MNB that I've not always been entirely honest about.
In the Air Force contract MNB provided the hardware only; for other customers it can provide customized software as well.
MNB was set up after the Russian Revolution as a foreign trade bank.
The court refused to hold MNB liable under either Sec.
Hungary's MNB cuts rates: On 25 September, the Hungarian National Bank (MNB) decided to lower its base rate in order to help the economy, which is in recession.
COVENTRY firm MNB Precision is a powerhouse - its products are used to make Formula 1 cars, space shuttles and deep-sea drilling rigs.
Coventry-based MNB Precision, which supplies to engineering firms in the oil, aerospace and machine tool manufacturing sectors, had grown into a business with a pounds 3.
The bank said, 'The MNB considers it important that the reduction of the bank tax should be accompanied with a significant rise in lending.