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a chemical element, atomic number 25, atomic weight 54.938. (See Appendix 6.) Its salts occur in the body tissue in very small amounts and serve as activators of liver arginase and other enzymes.
manganese poisoning a condition usually caused by inhalation of manganese dust; symptoms of chronic exposure include mental disorders accompanying a syndrome resembling Parkinson's disease, and inflammation throughout the respiratory system.
Symbol for manganese.
CA.1aj.9A gene on chromosome 9p12 that encodes a carbonic anhydrase, a zinc metalloenzyme that catalyses the reversible hydration of carbon dioxide. Carbonic anhydrases participate in various biological processes, including respiration, calcification, maintaining acid-base balance and bone resorption, as well as producing aqueous humour, cerebrospinal fluid, saliva and gastric acid. CA9 is a transmembrane protein and the only known tumour-associated carbonic anhydrase isoenzyme, and may be involved in cell proliferation and transformation.
CA9 is expressed in all clear-cell type renal cell carcinomas, but is not expressed in normal kidney or most other normal tissues.
Symbol for manganese