MMP19

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MMP19

A gene on chromosome 12q14 that encodes matrix metalloproteinase 19, an endopeptidase that degrades components of the extracellular matrix, including collagen IV, laminin, nidogen, nascin-C isoform, fibronectin and type I gelatin, playing a role in development, haemostasis and pathological conditions (e.g., arthritic disease). It is widely expressed except in the brain and peripheral white cells.
References in periodicals archive ?
To date, there is no published studies on MMP-19, MMP-20, MMP-23, MMP-27 and MMP-28 activity in renal tumours.
Besides MMP-2 and MMP-3, putative NLSs in the sequences of MMP-1, MMP-8, MMP-10, MMP-13, MMP-19, MMP20, and MMP-23 and MT1-MMP, MT3-MMP, MT4-MMP, and MT5-MMP were also detected [31], which suggests that nuclear entry may be a feature of many MMPs.
14) descreveram, apos estudo imuno-histoquimico, a presenca de MMP-19 em celulas basais do epitelio apos ceratites ulcerativas, porem sua exata funcao ainda nao foi estabelecida na cornea.