MALT1

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MALT1

A gene on chromosome 18q21 that encodes a protein which enhances BCL10-induced activation of NF-kappaB and is involved in nuclear export of BCL10. MALT1 binds to TRAF6, inducing TRAF6 oligomerisation and activation of its ubiquitin ligase activity; MALT1-dependent BCL10 cleavage plays an important role in T-cell antigen receptor-induced integrin adhesion.

Molecular pathology
MALT1 translocation t(11;18)(q21;q21) with BIRC2 occurs in ± 50% of cytogenetically abnormal low-grade MALT lymphomas.
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During the second phase, MLT1 training continued, involving lubrication mechanics and supervisors.
Currently, 80 Hibbing employees have received MLT1 training for machinery lubrication and basic oil analysis.
Interestingly, MLT1 recruits kids from a student technology organization called the iTeam to offer feedback and suggestions, as well as to volunteer their time to help instruct teachers on interactive alternatives that spike student interest, such as using a DVD instead of a textbook in a lesson about animals, or substituting a podcast for a standard chalkboard lecture.