CCL15

(redirected from MIP-1d)

CCL15

A gene on chromosome 17q11.2 that encodes a CC-type cytokine, which is characterised by two adjacent cysteines and, as with all cytokines, is involved in immunoregulatory and inflammatory processes. CCL15 is chemotactic for T cells and monocytes, and induces N-acetyl-beta-D-glucosaminidase release in monocytes; it also induces changes in intracellular calcium concentration in monocytes, is thought to act through the CCR1 receptor, and binds to CCR3.
References in periodicals archive ?
MIP-1d is chemotactic for neutrophils, monocytes, and lymphocytes and elicits its effects by binding to cell surface chemokine receptors.
(3) Chemokines: MIP-1d, MIP-3b, Eotaxin-1, Eotaxin-2, and BLC
We analyzed 13 markers which could be associated with preterm delivery IGFBP-1, IGFBP-2, BDNF, L-Selectin, E-Selectin, ICAM-1, PECAM, VCAM-1, MIP-1d, MIP-3b, Eotaxin-1, Eotaxin-2, and BLC, and we estimated their usefulness as markers for differentiation between threatened preterm delivery, preterm delivery, and false preterm delivery.
In our study, we found that other members of the chemokine family as MIP3b and MIP-1d could be associated with preterm delivery.
IGFBP-1: Insulin-like growth factor-binding protein 1 IGFBP-2: Insulin-like growth factor-binding protein 2 BDNF: Brain-derived neurotrophic factor L-Selectin: CD62L E-Selectin: CD62E ICAM-1: Intercellular adhesion molecule 1 PECAM: Platelet endothelial cell adhesion molecule VCAM-1: Vascular cell adhesion protein 1 MIP-1d: Chemokine (C-C motif) ligand 15 (CCL15) MIP-3b: Macrophage inflammatory protein-3 (CCL19) Eotaxin-1: C-C motif chemokine 11 (CCL11) Eotaxin-2: Chemokine (C-C motif) ligand 24 (CCL24) BLC: B lymphocyte chemoattractant.