MIF


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MIF

 [mif]

MIF

Abbreviation for migration-inhibitory factor.

MIF

A gene on chromosome 22q11.23 that encodes macrophage migration inhibitory factor (MMIF), a proinflammatory lymphokine involved in innate cell-mediated immunity, immunoregulation and inflammation, which regulates macrophage function in host defence by suppressing the anti-inflammatory effects of glucocorticoids.

Molecular pathology
Genetic variations of MIF have been linked to an increase in susceptibility to juvenile rheumatoid arthritis.
References in periodicals archive ?
MIF probably prevents cells in the bone marrow from responding to erythropoietin, the hormone that triggers red blood cell production, says coauthor Richard Bucala, an immunologist and rheumatologist at Yale University School of Medicine.
Briefly, to each designated, prewetted well on the filter plate, we added bead suspension (5-plex premixed beads and/or 5000 microspheres coated with suPAR, sTREM-1, or MIF antibody).
MIF is an important immunoregulatory protein with a unique ability to suppress the anti-inflammatory effects of steroids.
Tom Short, solicitor from law firm Leigh Day, added: "Our client is one of the many self-employed people suffering from the application of the MIF.
The MIF was created in 1978 as a separate operating unit of SONYMA and is made up of two accounts: the project pool account and the single-family account.
On the other hand, MIF is a multifunctional cytokine that acts as a major regulator of inflammation and a central upstream mediator of innate immune response [16].
Drug-affinity chromatography and surface plasmon resonance (SPR) biosensor technique showed that BTZO-1 and its active derivatives in both protection of rat primary cardiomyocyte from serum deprivation-induced cell death and ARE activation directly and selectively bound to MIF [32].
* The report provides a snapshot of the global therapeutic landscape for Macrophage Migration Inhibitory Factor (Glycosylation-Inhibiting Factor or L-Dopachrome Isomerase or MIF or EC 5.3.2.1)
The Multilateral Investment Fund (MIF), a member of the Inter-American Development Bank (IDB) Group, supports private sector-led development benefiting low-income populations and the poor--their businesses, their farms, and their households.
James T Harrington has announced his retirement as executive director of the Massachusetts Insurance Federation (MIF).
El factor inhibidor de la migracion de macrofagos (MIF) fue una de las primeras citocinas proinflamatorias que se describio en 1966, como un factor soluble expresado por linfocitos T en respuesta a la hipersensibilidad tipo retardada y ejerce un efecto inhibitorio sobre la migracion de los macrofagos in vitro (9, 10).
In 2013, remittances to Central America and the Caribbean increased over the previous year while remittance flows to South America and Mexico declined, resulting in flat growth for the region as a whole, according to a report from the Multilateral Investment Fund (MIF), a member of the Inter-American Development Bank (IDB) Group, reports Caribbean News Now (June 11, 2014):