MIC90


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MIC90

The maximum inhibitory concentration of an antibiotic, at which 90% of the isolates are inhibited
References in periodicals archive ?
The MIC90 values 0.20 mg/mL (2.8 mM) in this study were comparable with a variation towards higher side, but broth dilution assay had been used for determination of MIC.
However, further detailed pharmacodynamic studies of amoxicillin in Lohi sheep and Beetal goats are required to identify an actual as opposed to an assumed MIC90 for confirming the dose by generating sufficient data from field isolates in future studies before issuing final recommendations.
MIC90 of 178 isolates was compared by Cooper et al and found it to be 0.06ug/ml in 2001.
In 217 strains of CRAB from different patients, [MIC.sub.50] and MIC90 values were 0.5 and 1mg/L, respectively.
At each time peak, plasma drug concentrations were at or above the least inhibitory concentration (MIC90), whereas free drugs were cleared from the circulation within 12 hrs of oral administration [77].
The MIC90 of cefovecin against Staphylococcus intermedius was 0.25 microg/ml, for Escherichia col was 1.0 microg/ml and 0.06 microg/ml for Pasteurella multocida [13].
Table 1: Effect of medium pH levels on MICrange and MIC90 and the susceptibility percentage (Susc.%) of some antibiotics against B.
Antibiotic susceptibility in Kingella species isolates MIC50 MIC90 Amoxicillin 0.064 0.5 Cefotaxime 0.094 0.125 Ciprofloxacin 0.047 0.064 Meropenem 0.064 0.125 Trimethoprim-sulfamethoxazole 0.02 >32 Range Amoxicillin [less than or equal to] 0.016-0.5 Cefotaxime 0.032-0.125 Ciprofloxacin 0.016-0.064 Meropenem 0.008-0.125 Trimethoprim-sulfamethoxazole [less than or equal to] 0.02->32 % Susceptible K.
Many studies have found that most isolates are resistant to ampicillin [7, 9, 15-17, 26, 29, 51] with an MIC90 of 32mg/mL [17] and penicillin [9, 29], but susceptible to third- and fourth-generation cephalosporins, quinolones, aminoglycosides, and carbapenems [4,15-17, 38, 61].