MHC


Also found in: Dictionary, Thesaurus, Legal, Acronyms, Encyclopedia, Wikipedia.

complex

 [kom´pleks]
1. the sum, combination, or collection of various things or related factors, like or unlike; e.g., a complex of symptoms (see syndrome).
2. a group of interrelated ideas, mainly unconscious, that have a common emotional tone and strongly influence a person's attitudes and behavior.
3. that portion of an electrocardiographic tracing which represents the systole of an atrium or ventricle.
AIDS-related complex (ARC) a complex of signs and symptoms occurring in HIV infection including fever, weight loss, prolonged diarrhea, minor opportunistic infections, lymphadenopathy, and changes in cells of the immune system.
antigen-antibody complex here the complex formed by the noncovalent binding of an antibody and antigen. Complexes of antibodies belonging to certain immunoglobulin classes may activate complement. Called also immune complex.
anti-inhibitor coagulant complex (AICC) a concentrated fraction from pooled human plasma, which includes various coagulation factors. It is administered intravenously as an antihemorrhagic in hemophilic patients with inhibitors to coagulation factor VIII.
atrial complex the P wave of the electrocardiogram, representing electrical activity of the atria. See also ventricular complex.
castration complex in psychoanalytic theory, unconscious thoughts and motives stemming from fear of loss of the genitals as punishment for forbidden sexual desires.
Electra complex libidinous fixation of a daughter toward her father. This term is rarely used, since oedipus complex is generally applied to both sexes.
factor IX complex a sterile, freeze-dried powder consisting of partially purified coagulation factor IX fraction, as well as concentrated factor II, VII, and X fractions, of venous plasma from healthy human donors. It is used in the prophylaxis and treatment of bleeding in patients with hemophilia B, replacement of factor VII in patients deficient in that factor, and treatment of anticoagulant-induced hemorrhage. Administered intravenously.
Ghon complex primary complex (def. 1).
Golgi complex golgi apparatus.
HLA complex the human major histocompatibility complex, which contains the hla antigens.
immune complex antigen-antibody complex.
inclusion complex one in which molecules of one type are enclosed within cavities in the crystalline lattice of another substance.
inferiority complex unconscious feelings of inadequacy, producing shyness or timidity or, as a compensation, exaggerated agressiveness and expression of superiority; based on Alfred Adler's concept that everyone is born with a feeling of inferiority stemming from real or imagined physical or psychological deficiency, with the manner in which the inferiority is handled determining behavior.
interpolated premature ventricular complex a premature ventricular complex that does not interfere with the conduction of the next sinus beat, i.e., it lacks the usual following compensatory pause.
major histocompatibility complex (MHC) the chromosomal region containing genes that control the histocompatibility antigens; in humans it controls the hla antigens.
membrane attack complex (MAC) C5b,6,7,8,9, the five-molecule complex that is the cytolytic agent of the complement system.
Oedipus complex see oedipus complex.
primary complex
1. the combination of a parenchymal pulmonary lesion (Ghon focus) and a corresponding lymph node focus, occurring in primary tuberculosis, usually in children. Similar lesions may also be associated with other mycobacterial infections and with fungal infections.
2. the primary cutaneous lesion at the site of infection in the skin, e.g., chancre in syphilis and tuberculous chancre.
QRS complex a group of waves seen on an electrocardiogram, representing ventricular depolarization. Called also QRS wave. It actually consists of three distinct waves created by the passage of the cardiac electrical impulse through the ventricles and occurs at the beginning of each ventricular contraction. In a normal surface electrocardiogram the R wave is the upward deflection; the first downward deflection represents a Q wave and the final downward deflection is the S wave. The Q and S waves may be extremely weak and sometimes are absent.

One abnormality of the QRS complex is increased voltage resulting from enlargement of heart muscle, which produces increased quantities of electric current. A low-voltage QRS complex may result from toxic conditions of the heart, most commonly from fluid in the pericardium. Pleural effusion and emphysema also can cause a decrease in the voltage of the QRS complex.
VATER complex an association of congenital anomalies consisting of vertebral defects, imperforate anus, tracheoesophageal fistula, and radial and renal dysplasia.
ventricular complex the Q, R, S, and T waves of the electrocardiogram, representing ventricular electrical activity. See also atrial complex.

MHC

MHC

abbr.
major histocompatibility complex

MHC

Abbreviation for:
major histocompatibility complex
mental health course (Medspeak-UK) 
moisture holding capacity
multiphasic health checkup
myosin heavy chain 

Genetics
Major histocompatibility complex. A small region of the genome that is highly conserved in vertebrate evolution, which encodes three classes of polymorphic molecules known as the immune recognition unit. The MHC is located on the short arm of chromosome 6 in humans, and on chromosome 17 in mice. The products of the MHC gene complex are membrane-bound receptors for antigens and peptides which, when bound, are displayed to T cells; if the bound peptides are recognised by the T cells, an immune response against those peptides is initiated.

MHC

Major histocompatibility complex A small region of the genome that is highly conserved in vertebrate evolution, which encodes 3 classes of polymorphic molecules known as the immune recognition unit; the MHC is located on the short arm of chromosome 6 in humans; the products of the MHC gene complex are membrane-bound receptors for antigens and peptides which, when bound, are displayed to T cells; if the bound peptides are recognized by the T cells, an immune response against those peptidesis initiated

MHC

Abbreviation for major histocompatibility complex; minor histocompatibility complex.

MHC

Abbrev. for MAJOR HISTOCOMPATIBILITY COMPLEX.

MHC

Abbreviation for major histocompatibility complex.
References in periodicals archive ?
For developing discrimination models, ML algorithms are trained on data sets consisting of peptides that either bind or do not bind to MHC molecules.
In the MHC that was studied, the biweekly staffing sessions scheduled by judges illustrate the judges' role in designing a well-established MHC procedural justice system.
This leads to an ambiguous prediction of the effect of the MHC program in general relative to traditional Medicaid, but clear predictions for each of the two components separately.
MHCs are often paired with other reforms aimed at keeping the mentally ill out of jail.
[sz]2M deficient mutant has been derived in different models and changes of cellular and humoral responses are evaluated in these [sz]2M deficient animals.[sup][57] The mechanism of MHC I presenting peptides to CD8[sup]+ T-cell was shown in [Figure 1].
The MHC project forms part of the response to the invitation made by King Mohammed VI of Morocco during his visit to Abu Dhabi.
Primer design, amplification of MHC-DAB fragment and RACE-PCR amplification: A pair of degenerate primers, seMHC-N1 and seMHC-C1 (Table 1), were designed according to the conserved sequences of MHC II B genes from other species, such as large yellow croaker (ABV48908), striped sea bass (AAA49379), spotted halibut (GU253881), rainbow trout (AF115529) and cichlid (AAB27553).
The MHC furnished this writer the open letter thru e-mail on Saturday.
MHC: According to Chinese Ministry of Health's defining of Administration of Maternal Health Care MHC refers to medical care service provided for women (preparing for pregnancy or in 42 days within delivery) infants and fetal throughout the process by medical institutions at all levels.12 In this study MHC service utilization refers to women's utilization of antenatal care (ANC) hospital deliv- ery and postnatal visits.
MHC I and MHC II are highly variable in humans, because they both have multiple genes and each gene is highly polymorphic (Figure 3).
The next step was for the MHC to forward the proposal to the National Register, a division of the National Park Service, in Washington, D.C.
cbs.dtu.dk/services/NetMHCIIpan-2.0/) were used for the prediction of MHC I and MHC II binding epitopes of A(H1N1)pdm09 of Asian origin against MHC alleles that were predominantly found in Asian countries (De Groot, Sbai, Saint Aubin, McMurry and Martin, 2002, Reche and Reinherz, 2005).