CDK6(redirected from MGC59692)
CDK6A gene on chromosome 7q21-q22 that encodes a cyclin-dependent kinase, which is a catalytic subunit of the protein kinase complex important in cell cycle G1-phase progression and G1/S transition. CDK6, with CDK4, phosphorylates and regulates the activity of tumour suppressor protein Rb.
CDK6 expression is upregulated in some cancers.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.