PDE1A(redirected from MGC26303)
PDE1AA gene on chromosome 2q32.1 that encodes a cyclic nucleotide phosphodiesterase, which plays a critical role in signal transduction, regulating intracellular cyclic nucleotide concentrations by hydrolysing cAMP and/or cGMP to AMP and GMP. As with other PDE1s, PDE1A is activated by calmodulin in the presence of Ca2+.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.