LMX1B

(redirected from MGC138325)

LMX1B

A gene on chromosome 9q33.3 that encodes a member of the LIM-homeodomain family of proteins that acts as a transcription factor, and which is essential for the normal development of dorsal limb structures, glomerular basement membrane, anterior segment of the eye, and dopaminergic and serotonergic neurons.

Molecular pathology
LMX1B mutations cause nail-patella syndrome.
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