METAVIR scoring system

METAVIR scoring system

A system used to assess inflammation and fibrosis by histopathological evaluation of a liver biopsy of patients with hepatitis C. The grade indicates the activity or degree of inflammation, and the stage represents the amount of fibrosis or scarring.

Activity grade
• A0—No activity.
• A1—Mild activity.
• A2—Moderate activity.
• A3—Severe activity.
Fibrosis stage
• F0—No fibrosis.
• F1—Portal fibrosis without septa.
• F2—Portal fibrosis with few septa.
• F3—Numerous septa without cirrhosis.
• F4—Cirrhosis.
References in periodicals archive ?
Fibro-SURE (LabCorp), for example, uses a peripheral venous blood sample and combines the patient's age, gender, and 6 biochemical markers to generate a range of scores that correspond to the fibrosis component of the well-known METAVIR scoring system and correlate with results of liver biopsies.
Hepatitis C: screening changes, treatment advances
The patients were divided into two groups according to the stage of hepatic fibrosis using the METAVIR scoring system (F0-F2 vs.
Acute exacerbation of chronic hepatitis B virus infection in renal transplant patients
The Fibroscan (Echosense, Paris) was used for the measurement of liver stiffness and METAVIR scoring system was used for calculating liver stiffness measurement (LSM) values ranging from 3.
FIBROSCAN: A NON INVASIVE TOOL FOR PREDICTING EARLY ESOPHAGEAL VARICES IN CHRONIC LIVER DISEASE SECONDARY TO HEPATITIS C VIRUS INFECTION
Liver biopsies were analyzed for the fibrosis stage in each center by the local pathologist, using the METAVIR scoring system.
How to measure the diagnostic accuracy of noninvasive liver fibrosis indices: the area under the ROC curve revisited
The Metavir scoring system is a histological assessment of the degree of inflammatory activity and the stage of fibrosis.
Hepatitis C: how to fine-tune your approach
Re-examination of the liver biopsy classified the specimen as F1A2 according to the METAVIR scoring system.
Acute pancreatitis associated with boceprevir: a case report
The integrated database included published prospective studies of chronic hepatitis C patients with concomitant FT measurement and liver biopsy, who had liver biopsies scored using the METAVIR scoring system (5), had FT assessed on fresh serum using the recommended preanalytical and analytical procedures, and had individual data sent by the principal investigator.
Studies were included if fibrosis had been evaluated using the METAVIR scoring system, the diagnostic value was expressed using the AUC and the prevalence of different fibrosis stages was given.
A pathologist who was unaware of the biochemical markers evaluated the fibrosis stage and necrosis grade according to the METAVIR scoring system (5).
Standardization of ROC curve areas for diagnostic evaluation of liver fibrosis markers based on prevalences of fibrosis stages
Hepatic histological evaluation was graded and staged according to the Metavir scoring system.
Therapeutic effectiveness of biosimilar standard interferon versus pegylated interferon for chronic hepatitis C genotypes 2 or 3
who was unaware of the results for the biochemical markers, evaluated the stage of fibrosis and grade of activity according to the METAVIR scoring system (20, 21).
00, corresponding to stages FO-F4 and grades A0-A3 of the well-established METAVIR scoring system.
Prospective analysis of discordant results between biochemical markers and biopsy in patients with chronic hepatitis C
Medical browser ?
Full browser ?