Multiple endocrine neoplasia type 1

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Related to MEN I: Wermer's syndrome

MEN 1

An inherited neoplasia syndrome characterised by: parathyroid hyperplasia (95%), pituitary adenoma (10%), pancreatic islet hyperplasia, adenoma or carcinoma, and/or adrenal cortical hyperplasia, adenoma and carcinoid tumours.

Molecular pathology
Mutation of MEN1 on chromosome 11.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.

Multiple endocrine neoplasia type 1 (MEN-1)

An inherited condition marked by multiple malignancies of the pituitary gland, parathyroid gland, and islet cells of the pancreas. About half of MEN-1 patients with pancreatic islet cell tumors will have gastrinomas, gastrin-producing tumors that lead to ulcer disease.
Mentioned in: Gastrinoma
Gale Encyclopedia of Medicine. Copyright 2008 The Gale Group, Inc. All rights reserved.